Author

Xuancheng Lu

Chinese Center For Disease Control and PreventionORCID 0000-0002-0452-0834Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:multiome· 1 Assay:protein structure· 1 Approach:statistical model· 1

Frequent Co-Authors

Chaoyu ZhouiD· 1 shared George F. GaoiD· 1 shared Jianrui Zhao· 1 shared Jianxun QiiD· 1 shared Jiaqin CheniD· 1 shared Jing LiiD· 1 shared Meng-ao Jia· 1 shared Pei DuiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperPathology

Chaoyu ZhouORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Hepatitis E ORF2 blocks trophoblast autophagy to induce miscarriage via LC3B binding rather than PI3K/Akt/mTOR pathway suppression

Yinzhu Chen, Yifei Yang, Qianyu Bai, Xinyuan Tian, Chaoyu Zhou, Xuancheng Lu, Tianlong Liu

This study identifies that HEV ORF2 blocks trophoblast autophagy by binding LC3B, leading to miscarriage, independent of the PI3K/Akt/mTOR pathway.

Microorganisms · Jan 14, 2026Peer-reviewedPathology

Rational design of respiratory syncytial virus dimeric F-subunit vaccines in protein and mRNA forms

Jing Li, Xuehui Ma, Zepeng Xu, Wenjing Guo, Ruchao Peng, Yuqin Zhang, Yumin Meng, Jianrui Zhao, Qiyue Wang, Shuang Li, Jiaqin Chen, Yuxin Guo, Xuancheng Lu, Qingling Wang, Yushuang Guo, , Jianxun Qi

This study designs and tests dimeric RSV F-subunit vaccines in protein and mRNA forms, showing enhanced immunogenicity and protection against RSV infection in rodent models.

EBioMedicine · Aug 30, 2025Peer-reviewedImmunology