Author

Yi‐Kuo Yu

National Institutes of HealthORCID 0000-0002-6213-7665Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:proteomics· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Organism:C. elegans· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:E. coli· 1 Approach:experimental assay· 1

Frequent Co-Authors

Aleksey Y. OgurtsoviD· 3 shared Gelio AlvesiD· 3 shared Anthony S. BarenteiD· 1 shared Beatriz Piñeiro-IglesiasiD· 1 shared Björn AnderssoniD· 1 shared Daniel Jaén‐LuchoroiD· 1 shared Dustin L. Crockett· 1 shared Edward R. B. MooreiD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersBioinformatics

Aleksey Y. OgurtsovORCID

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3 papers

Recent·Most cited

BioinformaticsScientific ReportsPeer-reviewedAug 20, 2026

MARLOWE: Taxonomic Characterization of Unknown Samples for Forensics Using De Novo Peptide Identification

Sarah C. Jenson, Fanny Chu, Gelio Alves…·Kristin H. Jarman

MARLOWE is a computational tool for taxonomic characterization of unknown forensic samples using de novo peptide identification, achieving high specificity in species-level identification.

4 citations

proteomicsstatistical model

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BioinformaticsJournal of Proteome ResearchPeer-reviewedJul 18, 2025

Biological Function Assignment Across Taxonomic Levels in Mass-Spectrometry-Based Metaproteomics via a Modified Expectation Maximization Algorithm

Gelio Alves, Aleksey Y. Ogurtsov, Yi‐Kuo Yu

The paper improves biological function assignment in metaproteomics by modifying the EM algorithm in MiCId, showing better accuracy and false discovery control compared to existing tools.

4 citations

humanmetagenomics

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Systems BiologyJournal of the American Society for Mass SpectrometryPeer-reviewedMay 2, 2022

Identification of antibiotic resistance proteins via MiCId's augmented workflow. A mass spectrometry-based proteomics approach

Gelio Alves, Aleksey Y. Ogurtsov, Roger Karlsson…·Yi‐Kuo Yu

The paper introduces an augmented MiCId workflow for fast and accurate identification of antibiotic resistance proteins using mass spectrometry data, achieving high sensitivity and precision.

13 citations

E. coliC. elegans

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