Author

Laura Godfrey

University of OxfordORCID 0000-0002-6222-3563Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Laura Godfrey1 paper · University Hospital Cologne

Biology Disciplines

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Molecular Biology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell-cell communication· 2 Assay:ChIP-seq· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Assay:ATAC-seq· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Nicholas T. CrumpiD· 3 shared Thomas A. MilneiD· 3 shared Alastair SmithiD· 2 shared Emmanouela RepapiiD· 2 shared James O. J. DaviesiD· 2 shared Joe R. HarmaniD· 2 shared Ross ThorneiD· 2 shared A. Marieke OudelaariD· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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3 shared papersMolecular Biology

Nicholas T. CrumpORCID

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3 papers

Recent·Most cited

Molecular BiologyNature CommunicationsPeer-reviewedAug 25, 2023

PAF1 and FACT cooperate with MLL-AF4 to drive enhancer activity in leukemia

Nicholas T. Crump, Alastair Smith, Laura Godfrey…·Thomas A. Milne

This study identifies PAF1 and FACT as essential for enhancer activity in MLL-AF4-driven leukemia by maintaining histone acetylation and enhancer-promoter interactions.

27 citations

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Molecular BiologyNature CommunicationsPeer-reviewedJan 11, 2021

BET inhibition disrupts transcription but retains enhancer-promoter contact

Nicholas T. Crump, Erica Ballabio, Laura Godfrey…·Thomas A. Milne

The paper shows BET inhibition reduces transcription but not enhancer-promoter contacts, suggesting these processes are separable.

123 citationstop 1%

experimental assay

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Molecular BiologyNature CommunicationsPeer-reviewedJun 26, 2019

DOT1L inhibition reveals a distinct class ofenhancers dependent on H3K79 methylation

Laura Godfrey, Nicholas T. Crump, Ross Thorne…·Thomas A. Milne

The paper identifies a distinct class of enhancers in leukemia cells that depend on H3K79 methylation and shows that DOT1L inhibition disrupts their function.

151 citationstop 2%

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