Author

Yingzhi Wang

Chongqing Medical UniversityORCID 0000-0002-6229-2008Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Assay:protein structure· 1

Frequent Co-Authors

Chunlei Ge· 1 shared Congcong SheniD· 1 shared Fang Qu· 1 shared Hong Yao· 1 shared Hongfei Yi· 1 shared Hongwei LiuiD· 1 shared JuanJuan Yao· 1 shared Lin Hua· 1 shared

Activity by Year

2019-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBioengineering

Chunlei Ge

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2 papers

Recent·Most cited

De Novo Negatively Charged Binders Targeting MMLVRT Nucleic Acid Binding Sites Overcome Stability-Activity Trade-offs

Yibo Zhu, Hongwei Liu, Fang Qu, Yingzhi Wang, JuanJuan Yao, Shumin You, Lin Hua, Chunlei Ge, Hong Yao, Tao Li

This paper designs negatively charged binders that enhance the stability of MMLV RT without affecting its activity, overcoming stability-activity trade-offs.

bioRxiv · Mar 15, 2025 · PreprintBioengineering

Negative Cooperativity between Gemin2 and RNA provides Insights into RNA Selection and the SMN Complex's Release in snRNP Assembly

Hongfei Yi, Mu Li, Congcong Shen, Xi Kong, Yingzhi Wang, Yan Hou, Rundong Zhang

The paper shows negative cooperativity between Gemin2 and RNA in snRNP assembly, explaining RNA specificity and SMN complex release.

Nucleic Acids Research · Nov 21, 2019Peer-reviewedMolecular Biology