Deep screening of proximal and distal splicing-regulatory elements in a native sequence context
Yocelyn Recinos, Dmytro Ustianenko, Yow-Tyng Yeh, Xiaojian Wang, Martin Jacko, Lekha V. Yesantharao, Qiyang Wu, Chaolin Zhang
The paper develops SpliceRUSH, a high-throughput screening method to map splicing-regulatory elements in their native sequence context, identifying both known and novel SREs in the SMN2 gene.
bioRxiv · Aug 21, 2023 · PreprintMolecular Biology