Author

Chris Humphries

University of EdinburghORCID 0000-0002-6231-2603Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Anuruddika J FernandoiD· 1 shared Charlotte Potter· 1 shared James W. DeariD· 1 shared Janet Man· 1 shared Jennifer Ann CartwrightiD· 1 shared Justyna Cholewa-WaclawiD· 1 shared Kathleen ScullioniD· 1 shared Maria Elena CandelaiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperPharmacology & Toxicology

Anuruddika J FernandoORCID

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1 paper

Recent·Most cited

Pharmacology & ToxicologybioRxivPreprintSep 16, 2026

Non-invasive quantification of hepatic necrosis from circulating alanine aminotransferase kinetics in acetaminophen-treated mice in vivo

Chris Humphries, Jennifer Ann Cartwright, Rhona E. Aird…·Stuart John Forbes

This study uses serial ALT kinetics to estimate hepatic necrosis in vivo in acetaminophen-treated mice, showing better prediction accuracy than traditional methods and reducing animal use.

DOI 10.64898/2026.09.11.750627

mousebulk RNA-seq

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