Red Light-Activated Reversible Inhibition of Protein Functions by Assembled Trap
Peng Zhou, Yongkang Jia, Tianyu Zhang, Abasi Abudukeremu, Xuan He, Xiaozhong Zhang, Chao Liu, Wei Li, Zengpeng Li, Ling Sun, Shouhong Guang, Zhongcheng Zhou, Zhiheng Yuan, Xiaohua Lu, Yang Yu
The paper introduces R-LARIAT, a red light-induced protein clustering system that inhibits protein functions in HeLa cells by trapping GFP-tagged proteins, demonstrating high efficiency and stability.
ACS Synthetic Biology · Apr 30, 2025Peer-reviewedCell Biology