Rfx3 controls outer hair cell differentiation, maintenance, and hair bundle formation by regulating the expression of Insm1, Ikzf2, and Triobp genes
Penghui Zhang, Yafan Wang, Xiang Guo, Lu Ma, Xiangyao Zeng, Zhili Feng, Jinlei Liu, Mengzhen Yan, Yushan Gao, Jieran Dong, Junhong Li, Jie Ling, Hong Wu, Qianchen Jing, Yong Feng, Jun Li
This study identifies Rfx3's role in outer hair cell development by regulating Insm1, Ikzf2, and Triobp through transcriptional activation and repression.
bioRxiv · Sep 24, 2024 · PreprintDevelopmental Biology