Cancer BiologybioRxivPreprint
Dynamic estimation of metabolic state during CAR T cell production and the relationship of early metabolism to final therapeutic product
Narendra Suhas Jagannathan, Wei‐Xiang Sin, Denise Bei Lin Teo…·Rajeev J. Ram
This paper develops a modeling framework to estimate T cell metabolic rates during CAR T cell production and shows correlations between early metabolism and final product attributes.
DOI 10.1101/2025.05.11.653250