Cancer BiologyThe BreastPeer-reviewed
Multiscale Modeling Uncovers Macrophage Infiltration and TNF-α Signaling Networks for Targeting in Inflammatory Breast Cancer Tumor Emboli
Pritha PAI, Christophe Van Berckelaer, Steven Van Laere…·Gayathri R. Devi
This study identifies macrophage infiltration and TNF-α signaling networks in IBC tumor emboli and shows that targeting these pathways with Birinapant inhibits tumor emboli in vivo.