Hirotaka Ieki

This study shows that exosomes from human iPSC-cardiomyocytes and mesenchymal stem cells improve heart function after myocardial infarction in pigs, with distinct miRNA mechanisms.

This paper identifies new genetic loci for atrial fibrillation through a trans-ancestry meta-analysis and develops a polygenic risk score linked to cardioembolic risk.

This paper develops a deep learning model to estimate patient age and sex from chest X-rays, finding that CXR age correlates with cardiovascular aging and disease outcomes.

This study identifies three new CAD loci through transethnic GWAS and highlights population-specific genetic differences between Japanese and European populations.

This study identifies novel genetic loci for coronary artery disease in Japanese and transethnic populations and develops a polygenic risk score that outperforms population-specific scores.