BioinformaticsbioRxivPreprint
PertEval-scFM: Benchmarking Single-Cell Foundation Models for Perturbation Effect Prediction
Aaron Wenteler, Martina Occhetta, Nikhil Branson…·Amaya Gallagher-Syed
This study benchmarks zero-shot single-cell foundation model embeddings for perturbation effect prediction and finds they do not consistently improve over baseline models under distribution shift.