Molecular BiologyNucleic Acids ResearchPeer-reviewed
BRCA1-BARD1 combines multiple chromatin recognition modules to bridge nascent nucleosomes
Hayden Burdett, Martina Foglizzo, Laura J. Musgrove…·Marcus D. Wilson
This study investigates how the BRCA1-BARD1 complex interacts with chromatin containing specific histone modifications, showing it preferentially binds di-nucleosomes and uses multivalent interactions to overcome inhibitory marks.
24 citations