Author

George R. Heath

University of LeedsORCID 0000-0001-6431-2191Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:benchmarking· 1 Assay:ChIP-seq· 1 Approach:deep learning· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Assay:imaging· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

Ch. WältiiD· 1 shared Chalmers Chi Cheng ChauiD· 1 shared Daniel E. RollinsiD· 1 shared Dhananjay KumariD· 1 shared Elton ZeqirajiD· 1 shared Gillian CliffordiD· 1 shared Hayden BurdettiD· 1 shared Laura J. MusgroveiD· 1 shared

Activity by Year

2023-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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1 shared paperBiophysics

Ch. WältiORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

afMLevel: Deep learning U-Net Models for Levelling Atomic Force Microscopy Images and Movies

Maya Tekchandani, Daniel E. Rollins, Megan Westerell, Stephen D. Evans, Peter G. Adams, George R. Heath

This paper introduces two U-Net models for automatically levelling AFM images and movies, outperforming classical methods and reducing manual intervention.

bioRxiv · Oct 21, 2026 · PreprintBiophysics

Visualizing and Quantifying microRNA Induced DNA Origami Separation at the Nanoscale

Chalmers Chi Cheng Chau, Varun Gupta, George R. Heath, Ch. Wälti, Paolo Actis

This paper presents a method using DNA origami disassembly driven by miRNA to detect small RNA, showing robust detection in RNAse-containing environments.

Angewandte Chemie International Edition · Mar 13, 2026Peer-reviewedBiophysics

BRCA1-BARD1 combines multiple chromatin recognition modules to bridge nascent nucleosomes

Hayden Burdett, Martina Foglizzo, Laura J. Musgrove, Dhananjay Kumar, Gillian Clifford, Lisa J. Campbell, George R. Heath, Elton Zeqiraj, Marcus D. Wilson

This study investigates how the BRCA1-BARD1 complex interacts with chromatin containing specific histone modifications, showing it preferentially binds di-nucleosomes and uses multivalent interactions to overcome inhibitory marks.

Nucleic Acids Research · Sep 20, 2023Peer-reviewedMolecular Biology