Author

Philip S. Insel

University of California, San FranciscoORCID 0000-0002-6270-5490Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:differential expression· 2 Approach:statistical model· 2 Approach:Bayesian inference· 1 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1 Assay:proteomics· 1

Frequent Co-Authors

Michael DonohueiD· 2 shared Armin SchwartzmaniD· 1 shared David BerroniD· 1 shared Margo B. HestoniD· 1 shared Michelle Y. Li· 1 shared Niklas MattssoniD· 1 shared Oskar HanssoniD· 1 shared Paulina Tolosa‐TortiD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersNeuroscience

Michael DonohueORCID

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3 papers

Recent·Most cited

Genetic & Genomic MedicinemedRxivPreprintJun 15, 2026

Multi-domain AD risk burden and plasma biomarkers in cognitively unimpaired adults

Michelle Y. Li, Paulina Tolosa‐Tort, Margo B. Heston…·Shea J. Andrews

The paper examines how combined genetic, familial, and lifestyle risk factors affect plasma biomarkers in cognitively unimpaired adults, finding that higher risk burden correlates with specific biomarker changes.

DOI 10.64898/2026.06.11.26355499

humanproteomics

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NeurosciencebioRxivPreprintMar 10, 2021

Bayesian Multivariate Growth Mixture Modeling of Longitudinal Data: An Application to Alzheimer's Disease Study

Wenyi Lin, Michael Donohue, Philip S. Insel…·Wesley Kurt Thompson

The paper applies a Bayesian multivariate growth mixture model to identify cognitive decline patterns in Alzheimer's Disease Neuroimaging Initiative data.

3 citations

humanBayesian inference

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NeuroscienceNeuroImagePeer-reviewedDec 24, 2020

Time between milestone events in the Alzheimer's disease amyloid cascade

Philip S. Insel, Michael Donohue, David Berron…·Niklas Mattsson

The paper estimates the time-course of pathological markers and cognitive dysfunction in Alzheimer's disease relative to Aβ-positivity, finding tau and cognitive changes occur years before significant Aβ accumulation.

48 citations

humanbulk RNA-seq

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