Gilberto P. Pereira

The paper shows that human signal peptides are inefficiently cleaved by yeast SPCs due to differences in SPC-lipid interactions and membrane thinning profiles.

The paper introduces Auto-MartiniM3, a tool for automating the coarse-graining of small molecules for Martini 3 simulations, validated on 81 molecules and complex cases like caffeine.

The paper evaluates AlphaFold's ability to predict PROTAC-mediated protein interfaces and finds it struggles with small interfaces, impacting PROTAC design.

The paper presents a computational method to predict PROTAC-compatible protein-protein interfaces using docking and scoring techniques, achieving high accuracy in benchmark tests.