Author

Hongyan Guo

Louisiana State University Health Sciences Center ShreveportORCID 0000-0002-6286-1741Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Hongyan Guo2 papers · State Key Laboratory of Seed Innovation, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China

Biology Disciplines

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Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2

Frequent Co-Authors

Akhalesh Kumar ShakyaiD· 1 shared Benjamin R. BellenieiD· 1 shared Chang LiuiD· 1 shared Chaoran YiniD· 1 shared Heather S. KoehleriD· 1 shared Jason W. UptoniD· 1 shared Jian WangiD· 1 shared Joseph Yates· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperMicrobiology

Akhalesh Kumar ShakyaORCID

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2 papers

Recent·Most cited

MicrobiologybioRxivPreprintSep 28, 2026

Interferon gamma-induced MX1 and IFITM1 inhibit Varicella-Zoster Virus Replication

Seong K. Kim, Akhalesh Kumar Shakya, Hongyan Guo

This study identifies MX1 and IFITM1 as IFN-gamma-induced factors that inhibit VZV replication and shows JAK-STAT suppression promotes viral replication in keratinocytes.

DOI 10.64898/2026.09.28.754940

humanexperimental assay

Cell BiologyPLoS BiologyPeer-reviewedFeb 21, 2025

RIPK1 is essential for Herpes Simplex Virus-triggered ZBP1-dependent necroptosis in human cells

Oluwamuyiwa T. Amusan, Shuqi Wang, Chaoran Yin…·Hongyan Guo

This study shows that RIPK1 is essential for ZBP1-dependent necroptosis in human cells but not in mice, highlighting a species-specific mechanism.

36 citationstop 1%

humanexperimental assay