Chaoran Yin

This study compares Z22 and Z-D11 antibodies' binding to Z-NA substrates, finding they have distinct specificities and functional capabilities.

The paper presents cryo-EM structures of anti-Z-DNA antibodies bound to Z-DNA, revealing their recognition mechanism and lack of B-to-Z transition induction.

This study shows that RIPK1 is essential for ZBP1-dependent necroptosis in human cells but not in mice, highlighting a species-specific mechanism.