Single Cell RNA-sequencing of BCG naive and recurrent non-muscle invasive bladder cancer reveals a CD6/ALCAM mediated immune-suppressive pathway
Ivan Jurić, Emily E. Fink, Hong Qiu, P. Desprez, Arvind Ravi, Mark Holton, Vladimir Makarov, Nima Almassi, Booki Min, Gad A. Getz, Timothy An-thy Chan, Tyler Joseph Alban, Angela H. Ting, Byron Lee
This study uses single-cell RNA sequencing to identify a CD6/ALCAM-mediated immune-suppressive pathway in recurrent NMIBC, suggesting CD6 as a potential therapeutic target.
npj Precision Oncology · Sep 26, 2025Peer-reviewedCancer Biology