Presynaptic Gq-coupled receptors drive biphasic dopamine transporter trafficking that modulates dopamine clearance and motor function
Patrick J. Kearney, Nicholas C. Bolden, Elizabeth W. Kahuno, Tucker L. Conklin, Gilles E. Martin, Gert Lübec, Haley E. Melikian
This study shows that activating presynaptic Gq-coupled receptors causes biphasic DAT trafficking, affecting dopamine clearance and motor function.
Journal of Biological Chemistry · Jan 11, 2023Peer-reviewedNeuroscience