Author

Jean‐Pierre Raufman

University of Maryland, BaltimoreORCID 0000-0002-6340-4382Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Alyssa SchledwitziD· 1 shared Andrew Hui· 1 shared Christopher J. BridgemaniD· 1 shared Daniel H. LevyiD· 1 shared Emily H. PowsneriD· 1 shared Laura Samantha C. Reus· 1 shared Mitali Sarkar· 1 shared Natalia Sampaio MouraiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBioengineering

Alyssa SchledwitzORCID

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1 paper

Recent·Most cited

Genetically-programmed Hypervesiculation of Lactiplantibacillus plantarum Increases Production of Bacterial Extracellular Vesicles with Therapeutic Efficacy in a Preclinical Inflammatory Bowel Disease Model

Nicholas H. Pirolli, Daniel H. Levy, Alyssa Schledwitz, Natalia Sampaio Moura, Mitali Sarkar, Talia J. Solomon, Emily H. Powsner, Raith Nowak, Zuzanna Mamczarz, Christopher J. Bridgeman, Sulayman Khan, Andrew Hui, Nidhi Anne, Laura Samantha C. Reus, William E. Bentley, , Steven M. Jay

This study genetically engineers Lactiplantibacillus plantarum to produce 66-fold more extracellular vesicles, which show superior therapeutic efficacy in a mouse model of inflammatory bowel disease.

Advanced Science · Nov 26, 2025Peer-reviewedBioengineering