Designing AI-programmable therapeutics with the EDEN family of foundation models
Geraldene Munsamy, Gavin Ayres, Carla Greco, Keith Y K Kam, Gus Minto-Cowcher, John St John, Tanggis Bohnuud, Matthew H. Bakalar, William Chow, Robert J. Pecoraro, Marcelo D. T. Torres, Aaron W. Kollasch, Marcus H. Y. Leung, Hassan Sirelkhatim, Francesco Farina, , Philipp Lorenz
This paper introduces the EDEN family of foundation models for AI-programmable therapeutic design, demonstrating their ability to generate functional gene insertions, antibiotic peptides, and synthetic microbiomes.
bioRxiv · Feb 9, 2026 · PreprintGenomics