Systems BiologymSystemsPeer-reviewed
The slowdown of growth rate controls the single-cell distribution of biofilm matrix production via a SinI-SinR-SlrR network
Zhuo Chen, Brenda Zarazúa‐Osorio, Priyanka Srivastava…·Oleg A. Igoshin
This study uses mathematical modeling and experiments to show that growth rate fluctuations and bistability in a regulatory network explain single-cell heterogeneity in biofilm matrix production and sporulation in Bacillus subtilis.
14 citations