Author

Julia R. Widom

University of OregonORCID 0000-0002-6357-2749Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:protein folding & dynamics· 2 Research Focus:chromatin & epigenetic regulation· 1 Assay:fluorescence / live-cell microscopy· 1 Approach:microscopy & imaging analysis· 1 Assay:proteomics· 1

Frequent Co-Authors

Madison KadrmasiD· 2 shared Nico E. Conoan NievesiD· 2 shared Taylor L. CoulsoniD· 2 shared Abigail L VaaleriD· 1 shared Aimee M. MartiniD· 1 shared David M. GarciaiD· 1 shared Emily M. DennisiD· 1 shared Gavin A. ValdeziD· 1 shared

Activity by Year

2024-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersBiophysics

Madison KadrmasORCID

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Author profile →

5 papers

Recent·Most cited

Pyrrolocytosine as a Fluorescent Sensor of RNA-Small Molecule Interactions

Taylor L. Coulson, Gavin A. Valdez, Julia R. Widom

This study uses pyrrolocytosine (pC) as a fluorescent sensor to detect RNA-small molecule interactions, showing it can distinguish between similar ligands based on hydrogen bonding.

International Journal of Molecular Sciences · Oct 28, 2026Peer-reviewedBiophysics

Alternative probe chemistries for single-molecule analysis of long non-coding RNA

Kalika R. Pai, Aimee M. Martin, Madison Kadrmas, Julia R. Widom

This study evaluates alternative probe chemistries for SiM-KARTS to improve the analysis of lncRNA structure and dynamics.

Journal of Biological Chemistry · Apr 9, 2026Peer-reviewedBiophysics

Chronology of tRNA structural dynamics prior to and during interaction with a pseudouridine synthase

Emily M. Dennis, Nico E. Conoan Nieves, Madison Kadrmas, Abigail L Vaaler, Margaret L. Barry, David M. Garcia, Julia R. Widom

The paper uses single-molecule techniques to study tRNA structural dynamics before and during interaction with the pseudouridine synthase Pus4, revealing conformational changes and remodeling effects.

RNA · Mar 31, 2026Peer-reviewedBiophysics

Impacts of sequence and structure on pyrrolocytosine fluorescence in RNA

Taylor L. Coulson, Julia R. Widom

This paper investigates how sequence and structure affect the fluorescence of pyrrolocytosine (pC) in RNA, showing that pC is brightest in base-stacked, unpaired conformations.

Nucleic Acids Research · Mar 23, 2025Peer-reviewedBiophysics

Ligand binding characteristics of an NAD+ riboswitch revealed by FRET and biolayer interferometry

Nico E. Conoan Nieves, Julia R. Widom

The paper uses FRET and biolayer interferometry to study how NAD+ riboswitches bind β-NMN, showing changes in pseudoknot structure with ligand and Mg2+.

Chemical Communications · Nov 19, 2024Peer-reviewedBiophysics