Author

Megan Cole

The Francis Crick InstituteORCID 0000-0002-6366-0642Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:host-pathogen & immune response· 1 Approach:microscopy & imaging analysis· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Alastair J. MagnessiD· 1 shared Andrea de CastroiD· 1 shared Asher MullokandoviD· 1 shared Charles SwantoniD· 1 shared Chris MooreiD· 1 shared Claudia LeeiD· 1 shared Edurne MugarzaiD· 1 shared Emma ColliveriD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Alastair J. MagnessORCID

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1 paper

Recent·Most cited

Spatial proteomic analysis of a lung cancer model reveals regulatory T cells attenuate KRAS-G12C inhibitor-induced immune responses

Megan Cole, Panayiotis Anastasiou, Claudia Lee, Xiaofei Yu, Andrea de Castro, Jannes Roelink, Chris Moore, Edurne Mugarza, Martin L. Jones, Karishma Valand, Sareena Rana, Emma Colliver, Mihaela Angelova, Katey S.S. Enfield, Alastair J. Magness, , Febe van Maldegem

The paper identifies regulatory T cells as mediators of resistance to KRAS-G12C inhibitors and anti-PD-1 therapy through spatial proteomic analysis of lung cancer models.

Science Advances · Nov 1, 2024Peer-reviewedCancer Biology