MicrobiologyScience AdvancesPeer-reviewed
Secreted ORF8 reprograms macrophages to enhance SARS-CoV-2 infection of lung epithelial cells
Yusuke Matsui, Rahul K. Suryawanshi, Mauricio Montaño…·Mélanie Ott
This study shows that SARS-CoV-2's ORF8 protein reprograms macrophages to enhance viral infection of lung epithelial cells, contributing to lung pathology in COVID-19.
DOI 10.1126/sciadv.aee5421