BiochemistrybioRxivPreprint
Deciphering the Role of Acetate in Metabolic Adaptation and Drug Resistance in Non-Small Cell Lung Cancer
Giorgia Maroni, Eva Cabrera San Millán, Beatrice Campanella…·Emilia Bramanti
This study identifies a metabolic adaptation in osimertinib-resistant NSCLC cells involving acetate production via a PAA shunt, which supports redox balance and bioenergetics.
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