Loïc Mangnier

The paper shows that CTCF loss in mouse heart cells reorganizes enhancer activity-by-contact scores, reduces CRH numbers, increases CRH size, and increases CRH crossing TAD boundaries.

RetroFun-RVS is a family-based rare-variant analysis method that integrates functional annotations to improve power and interpretability in complex disease studies.

This paper benchmarks nineteen methods for integrating metagenomics and metabolomics data, identifies top-performing approaches, and provides guidelines for their application.

The paper introduces cis-regulatory hubs (CRHs) as a 3D model of gene regulation in neurons, showing their enrichment in schizophrenia-associated genes, SNPs, and heritability.

The paper benchmarks DIA acquisition methods and software tools using a complex proteomic standard, identifying optimal workflows for LC-MS/MS proteomic analyses.