Steve Bilodeau

CTCF mediates the Activity-by-contact derived cis-regulatory hubs

The paper shows that CTCF loss in mouse heart cells reorganizes enhancer activity-by-contact scores, reduces CRH numbers, increases CRH size, and increases CRH crossing TAD boundaries.

BioDiscViz : a visualization support and consensus signature selector for BioDiscML results

BioDiscViz provides visualization tools and consensus signature selection for BioDiscML results to improve model interpretation and usability.

Cis-Regulatory Hubs: a new 3D Model of Complex Disease Genetics with an Application to Schizophrenia

The paper introduces cis-regulatory hubs (CRHs) as a 3D model of gene regulation in neurons, showing their enrichment in schizophrenia-associated genes, SNPs, and heritability.

Genes on Different Strands Mark Boundaries Associated with Co-regulation Domains

The paper investigates how gene orientation and position influence co-regulation domains (CODs) within topologically associating domains (TADs) using RNA-seq, ChIP-seq, and Hi-C data from A549 cells.