Author

Hira Mazhar

The University of Texas MD Anderson Cancer CenterORCID 0000-0002-6400-5498Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:mouse· 1 Research Focus:perturbation response prediction· 1

Frequent Co-Authors

Manu M. SebastianiD· 1 shared Nicholas BlazaniniD· 1 shared Phuong Kieu Nguyen· 1 shared Sasikumar Kotagiri· 1 shared Xiaobing Liang· 1 shared Yanyan HaniD· 1 shared Yawen WangiD· 1 shared Yonathan LissanuiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperCancer Biology

Manu M. SebastianORCID

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1 paper

Recent·Most cited

Cancer BiologyJournal of Medicinal ChemistryPeer-reviewedApr 25, 2025

Discovery of Novel, Potent and Orally Bioavailable SMARCA2 PROTACs with Synergistic Anti-tumor Activity in Combination with KRAS G12C Inhibitors.

Sasikumar Kotagiri, Yawen Wang, Yanyan Han…·Yonathan Lissanu

This paper discovers and characterizes potent SMARCA2 PROTACs that show anti-tumor activity and synergize with KRAS G12C inhibitors in SMARCA4 mutant lung cancer.

12 citations

mouseexperimental assay

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