Scalable Human Cellular Models of Parkinson Disease Reveal A Druggable Link Between the Angiotensin Receptor 1 and Alpha-Synuclein Pathology
Mathieu Daynac, Vincent Mouilleau, Yuxi Liu, Xiaoyu Yang, Yin Shen, Su Guo
This study uses human iPSC-derived models to show AGTR1 inhibition protects mDA neurons from degeneration and reduces alpha-synuclein pathology.
bioRxiv · Nov 18, 2025 · PreprintNeuroscience