BiophysicsNature CommunicationsPeer-reviewed
Translational T-box riboswitches bind tRNA by modulating conformational flexibility
Eduardo Campos-Chávez, Sneha Paul, Zunwu Zhou…·Alfonso Mondragón
This study uses single-molecule FRET to analyze the binding mechanism of the Mycobacterium tuberculosis IleS T-box riboswitch, revealing a two-step model and the role of specific sequences in conformational flexibility and tRNA recognition.
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