Widespread AAV-mediated CSPG digestion impairs functional recovery after cervical spinal cord injury
Mariajose Metcalfe, Oswald Steward, Daisy Gallardo
This study investigates the effects of AAV-mediated CSPG digestion and PTEN knockdown on functional recovery after cervical spinal cord injury, finding that CSPG degradation alone or combined with PTEN suppression impairs motor function.
bioRxiv · May 26, 2026 · PreprintNeuroscience