Cancer Biologynpj Genomic MedicinePeer-reviewed
CDK4 is co-amplified with either TP53 promoter gene fusions or MDM2 through distinct mechanisms in osteosarcoma
Karim H. Saba, Valeria Difilippo, Emelie Styring…·Karolin H. Nord
This study identifies four subgroups of osteosarcomas based on genomic and transcriptomic analysis, revealing distinct mechanisms of CDK4 amplification in relation to MDM2 or TP53 alterations.
9 citations