BioengineeringActa BiomaterialiaPeer-reviewed
Recapitulating Patient-to-Patient Colorectal Cancer Tumor Heterogeneity Using Patient-Derived Xenograft Cells in an Engineered Tissue Model
Iman Hassani, Benjamin Anbiah, Yuan Tian…·Elizabeth A. Lipke
This study develops 3D-eCRC-PDX tissues to recapitulate patient-specific tumor heterogeneity, showing they maintain growth rates, cell subpopulations, mechanical stiffness, and gene expression profiles.
1 citation