Author

Yuan Tian

Auburn University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Bioengineering· 1 Evolutionary Biology· 1 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1

Frequent Co-Authors

Aiping MaoiD· 1 shared Benjamin AnbiahiD· 1 shared Bulbul AhmediD· 1 shared Elizabeth A. LipkeiD· 1 shared Elliot J. LefkowitziD· 1 shared Gang ZouiD· 1 shared Iman HassaniiD· 1 shared Kuan SuniD· 1 shared

Activity by Year

2015-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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1 shared paperGenetic & Genomic Medicine

Aiping MaoORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Berrylyzer-an Efficient, Traceable, and Lightweight Intelligent Agentic System for Prenatal Genetic Diagnosis

Meng Meng, Ling Liu, Qianqian Du, Xinyao Zhou, Yuan Tian, Kuan Sun, Naiqi Li, Pinggui Zhang, Xianyi Lian, Ning Fan, Na Zhu, Shujing Li, Aiping Mao, Yuezhen Li, Gang Zou

Berrylyzer is a variant prioritization system for prenatal genetic diagnosis that outperforms existing tools in ranking diagnostic variants and recall rates.

medRxiv · Apr 4, 2026 · PreprintGenetic & Genomic Medicine

Recapitulating Patient-to-Patient Colorectal Cancer Tumor Heterogeneity Using Patient-Derived Xenograft Cells in an Engineered Tissue Model

Iman Hassani, Benjamin Anbiah, Yuan Tian, Bulbul Ahmed, William Van Der Pol, Elliot J. Lefkowitz, Peyton C. Kuhlers, Nicole L. Habbit, Martin J. Heslin, Michael W. Greene, Elizabeth A. Lipke

This study develops 3D-eCRC-PDX tissues to recapitulate patient-specific tumor heterogeneity, showing they maintain growth rates, cell subpopulations, mechanical stiffness, and gene expression profiles.

Acta Biomaterialia · Feb 27, 2026Peer-reviewedBioengineering

Distribution of gene tree histories under the coalescent model with gene flow

Yuan Tian, Laura S. Kubatko

The paper introduces a coalescent model with gene flow between three species and shows that gene tree history distributions can identify species tree parameters, while topologies cannot, using simulations and empirical data.

bioRxiv · Aug 10, 2015 · PreprintEvolutionary Biology