Author

Alan O. Gao

University of CopenhagenORCID 0000-0002-6446-4889Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1

Frequent Co-Authors

Irene GallinaiD· 1 shared Johannes C. WalteriD· 1 shared Julien P. DuxiniD· 1 shared Justin L. Sparks· 1 shared Markus RäschleiD· 1 shared Matthias ManniD· 1 shared Nicolai Balle LarseniD· 1 shared

Activity by Year

2018-2018 · peak 1/yr

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7 top collaborators · 21 mutual co-author links

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1 shared paperMolecular Biology

Irene GallinaORCID

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1 paper

Recent·Most cited

Mechanism of replication-coupled DNA-protein crosslink proteolysis by SPRTN and the proteasome

Alan O. Gao, Nicolai Balle Larsen, Justin L. Sparks, Irene Gallina, Matthias Mann, Markus Räschle, Johannes C. Walter, Julien P. Duxin

This study shows that both SPRTN and the proteasome degrade DNA-protein crosslinks during DNA replication, using distinct mechanisms involving ubiquitylation and polymerase extension.

bioRxiv · Aug 1, 2018 · PreprintMolecular Biology