Author

Irene Gallina

University of CopenhagenORCID 0000-0002-3741-9038Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 1

Frequent Co-Authors

Julien P. DuxiniD· 2 shared Alan O. GaoiD· 1 shared Alberto Carli· 1 shared Bente BenedictiD· 1 shared Bob MeeuseniD· 1 shared Daniel R. SemlowiD· 1 shared Emil Peter Thrane HertziD· 1 shared Ivo Alexander HendriksiD· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersMolecular Biology

Julien P. DuxinORCID

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2 papers

Recent·Most cited

Catalytic and non-catalytic functions of DNA polymerase kappa in translesion DNA synthesis

Selene Sellés‐Baiget, Sara M. Ambjørn, Alberto Carli, Ivo Alexander Hendriks, Irene Gallina, Norman E. Davey, Bente Benedict, Bob Meeusen, Emil Peter Thrane Hertz, Laura Slappendel, Daniel R. Semlow, Sampath Amitash Gadi, Shana J. Sturla, Michael Lund Nielsen, Jakob Nilsson, , Julien P. Duxin

This study identifies catalytic and non-catalytic functions of DNA polymerase kappa in translesion DNA synthesis using CRISPR screening and TLS analysis.

bioRxiv · Nov 6, 2023 · PreprintMolecular Biology

Mechanism of replication-coupled DNA-protein crosslink proteolysis by SPRTN and the proteasome

Alan O. Gao, Nicolai Balle Larsen, Justin L. Sparks, Irene Gallina, Matthias Mann, Markus Räschle, Johannes C. Walter, Julien P. Duxin

This study shows that both SPRTN and the proteasome degrade DNA-protein crosslinks during DNA replication, using distinct mechanisms involving ubiquitylation and polymerase extension.

bioRxiv · Aug 1, 2018 · PreprintMolecular Biology