The Staphylococcus aureus prophage-encoded SSBP attenuates virulence and enhances IL-6-mediated macrophage clearance
Nour Ahmad-Mansour, Cynthia N. Abi Najem, Marianne Martin, Lucile Plumet, Sylvaine Huc-Brandt, Madjid Morsli, Patrice François, Albert Sotto, Catherine Dunyach‐Remy, Jean‐Philippe Lavigne, Virginie Molle
This study identifies a prophage-encoded SSBP that reduces S. aureus virulence and enhances macrophage-mediated bacterial clearance through IL-6 activation.
bioRxiv · Mar 13, 2025 · PreprintMicrobiology