Author

Aya Mikdache

Centre National de la Recherche ScientifiqueORCID 0000-0002-6468-1947Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 4 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:mouse· 3 Organism:zebrafish· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Research Focus:clustering· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

Gwendoline Gros· 3 shared Patricia Diabangouaya· 3 shared Pedro P. HernándeziD· 3 shared Akshai Janardhana KurupiD· 2 shared Camila Garcia-BaudinoiD· 2 shared Cindy DegernyiD· 2 shared Marcel TawkiD· 2 shared Marie‐José BoueidiD· 2 shared

Activity by Year

2022-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersDevelopmental Biology

Gwendoline Gros

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5 papers

Recent·Most cited

Developmental BiologybioRxivPreprintSep 18, 2025

Sox2 Regulates Lateral Line Morphogenesis via Yap/Taz-Mediated Mechanotransduction

Akshai Janardhana Kurup, Aya Mikdache, Nachoi Mokhtar…·Pedro P. Hernández

This study identifies Sox2 as a regulator of lateral line morphogenesis in zebrafish by modulating Yap/Taz-mediated mechanotransduction and cell proliferation.

DOI 10.1101/2025.09.18.677037

zebrafishexperimental assay

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ImmunologybioRxivPreprintApr 25, 2025

Interleukin-22 in enteroendocrine cells controls early-life gut motility through interactions with the microbiota

Soraya Rabahi, Emiliano Marachlian, Fabian Guendel…·Pedro P. Hernández

This study shows that IL-22 from enteroendocrine cells in zebrafish larvae controls gut microbiota and motility, with similar effects observed in mice.

DOI 10.1101/2025.04.25.650580

zebrafishmouse

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Developmental BiologybioRxivPreprintFeb 19, 2024

Schwann cells have a limited window of time in which to initiate myelination program during early migration in vivo

Océane El-Hage, Aya Mikdache, Marie‐José Boueid…·Marcel Tawk

The paper shows that Schwann cells must initiate myelin signaling during a specific time window in vivo, and missing this window prevents myelination.

DOI 10.1101/2024.02.19.580938

mouseexperimental assay

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Developmental BiologybioRxivPreprintJun 23, 2023

A non-invasive photoactivatable split-Cre recombinase system for genome engineering in zebrafish.

Ramy Elsaid, Aya Mikdache, Patricia Diabangouaya…·Pedro P. Hernández

This paper develops a non-invasive light-inducible split-Cre system for precise genome engineering in zebrafish.

1 citation

zebrafishexperimental assay

𝕏 PostBluesky

Developmental BiologybioRxivPreprintFeb 11, 2022

Timely Schwann cell division during migration drives peripheral myelination in vivo via Laminin/cAMP pathway

Aya Mikdache, Marie‐José Boueid, Emilie Lesport…·Marcel Tawk

This study identifies the role of Sil in regulating timely Schwann cell division during migration, which is essential for myelination via the Laminin/cAMP pathway.

1 citation

mouseexperimental assay

𝕏 PostBluesky