Bruce A. Bowerman

The paper identifies temperature-sensitive embryonic-lethal mutants in C. elegans with morphogenesis defects and characterizes their genetic and cellular basis.

The paper introduces MIP-MAP, a method to map temperature-sensitive mutations in C. elegans using molecular inversion probes, achieving high-resolution genetic mapping with high-throughput sequencing.

The paper identifies extracellular cues that tune actomyosin flows to orient cell division axes in C. elegans and mouse embryos.