Laura E. Been

{triangleup}FOSB in the nucleus accumbens core is required for increased anxiety, but not decreased social motivation, following estrogen withdrawal in female mice

This study shows that increased {Delta}FOSB in the nucleus accumbens core during estrogen withdrawal in female mice is necessary for heightened anxiety but not reduced social motivation.

Long-Term Oral Tamoxifen Administration Decreases Brain Derived Neurotrophic Factor in the Hippocampus of Female Long-Evans Rats

This study shows that long-term oral tamoxifen reduces BDNF in the hippocampus of female rats, suggesting a potential mechanism for cognitive side effects in patients.

Elevated estradiol during a hormone simulated pseudopregnancy decreases sleep and increases hypothalamic activation in female Syrian hamsters

Postpartum estrogen withdrawal induces deficits in affective behaviors and increases ΔFosB in D1 and D2 neurons in the nucleus accumbens core in mice

This study shows that postpartum estrogen withdrawal in mice increases anxiety-like behavior and ΔFosB expression in nucleus accumbens D1 and D2 neurons.

Estrogen withdrawal alters oxytocin signaling in the paraventricular hypothalamus and dorsal raphe nucleus to increase postpartum anxiety

This study shows that estrogen withdrawal increases anxiety-like behaviors by altering oxytocin signaling in the paraventricular hypothalamus and dorsal raphe nucleus in Syrian hamsters.