Electrostatic interactions in nucleosome and higher-order structures are regulated by protonation state of histone ionizable residue
Houfang Zhang, Wenhan Guo, Wang Xu, Anbang Li, Lijun Jiang, Lin Li, Yunhui Peng
The paper investigates how changes in histone protonation states affect nucleosome electrostatic potentials and interactions with partner proteins, and how cancer mutations influence these interactions.
The Journal of Chemical Physics · Mar 12, 2025Peer-reviewedBiophysics