Author

Houfang Zhang

Central China Normal UniversityORCID 0009-0004-3308-5933Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 2 Approach:mechanistic / dynamical model· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1 Approach:statistical model· 1 Assay:structural biology· 1

Frequent Co-Authors

Yunhui PengiD· 2 shared Anbang LiiD· 1 shared Anna R. PanchenkoiD· 1 shared Catherine A. MusselmaniD· 1 shared Harrison A. FuchsiD· 1 shared Lijun JiangiD· 1 shared Lin LiiD· 1 shared Ruben Rosas· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBiophysics

Yunhui PengORCID

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2 papers

Recent·Most cited

G34R cancer mutation alters the conformational ensemble and dynamics of the histone H3.3 tails

Harrison A. Fuchs, Yunhui Peng, Shine Ayyapan, Ruben Rosas, Houfang Zhang, Anna R. Panchenko, Catherine A. Musselman

This study examines how the G34R and G33R mutations in histone H3.3 affect nucleosome structure and dynamics using NMR and molecular dynamics simulations.

Nucleic Acids Research · Nov 23, 2025Peer-reviewedBiophysics

Electrostatic interactions in nucleosome and higher-order structures are regulated by protonation state of histone ionizable residue

Houfang Zhang, Wenhan Guo, Wang Xu, Anbang Li, Lijun Jiang, Lin Li, Yunhui Peng

The paper investigates how changes in histone protonation states affect nucleosome electrostatic potentials and interactions with partner proteins, and how cancer mutations influence these interactions.

The Journal of Chemical Physics · Mar 12, 2025Peer-reviewedBiophysics