Author

Hao Zhu

Beihang UniversityORCID 0000-0002-6507-8904Unclaimed ORCID profile · follow to get notified of new preprints

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Hao Zhu8 papers · Chinese University of Hong Kong

Biology Disciplines

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Bioinformatics· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Baichuan XiaoiD· 2 shared Jiqiang LiuiD· 2 shared Ruirui Lang· 2 shared Ziqiu Meng· 2 shared Bingqing WangiD· 1 shared Chao LiuiD· 1 shared Chao Ma· 1 shared Daiyi Liu· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersBioinformatics

Baichuan XiaoORCID

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2 papers

Recent·Most cited

Discovery of potent oligopeptides for various metabolic diseases using deep learning

Baichuan Xiao, Hao Zhu, Chao Ma, Xiaoran WANG, Zhanying Feng, Ruirui Lang, Hailin Shan, Ziqiu Meng, Runbang He, Yixiang Zhou, J. Huang, Siyang Wei, Daiyi Liu, Jiqiang Liu, Zhenni Shi, , Yong-Biao Zhang

This paper introduces Deepeptide, a deep learning pipeline that identifies therapeutic oligopeptides for metabolic diseases, finding 62% of candidates show significant in vitro bioactivity comparable to first-line drugs.

bioRxiv · Jan 7, 2026 · PreprintBioinformatics

Dysregulation in Spatiotemporal Expression of HMX1 Coordinated by Multifaceted Enhancers Drives an Auricular Disorder

Xiaopeng Xu, Qi Chen, Qingpei Huang, Timothy C. Cox, Hao Zhu, Jintian Hu, Xi Han, Ziqiu Meng, Bingqing Wang, Zhiying Liao, Wenxin Xu, Baichuan Xiao, Ruirui Lang, Jiqiang Liu, Qiang Li, , Yong‐Biao Zhang

This study identifies a CNV involving three enhancers that drive bilateral constricted ear malformations by coordinating HMX1 expression through distinct regulatory mechanisms.

bioRxiv · Apr 1, 2024 · PreprintDevelopmental Biology