Qi Chen

The paper profiles RNA content in P-bodies across vertebrate species, showing that RNA sequestration in condensates is linked to cell fate transitions through miRNA-dependent mechanisms.

This study identifies a CNV involving three enhancers that drive bilateral constricted ear malformations by coordinating HMX1 expression through distinct regulatory mechanisms.

The paper shows that the SHP1-C453S mutant, which lacks catalytic activity, has enhanced liquid-liquid phase separation (LLPS) ability, suggesting a link between conformational changes and LLPS.

CRISPR-Detector detects, visualizes, and annotates genome-wide mutations from CRISPR/Cas gene editing events with improved speed, scalability, and accuracy.

The paper proposes a standardized ontology for naming tRNA-derived RNAs based on molecular origin to improve inter-study comparisons.

This study uses low-input ribosome profiling to analyze translational selectivity in bovine oocytes and preimplantation embryos, revealing four modes of translational regulation and their temporal dynamics.

This study conducts a genome-wide association meta-analysis of childhood aggression across multiple raters, instruments, and ages, identifying genetic correlations with various traits but no genome-wide significant SNPs.

The paper shows that sperm cooperation in mice forms clusters at the utero-tubal junction, facilitating oviduct entry and fertilization, with defects in this process linked to infertility.

The paper investigates circRNA expression across tissues and developmental stages in rats, finding unique age-dependent patterns in testes linked to spermatogenesis.

SPORTS1.0 annotates and profiles non-coding RNAs, including rRNA- and tRNA-derived sRNAs, and identifies RNA modification sites from sRNA-seq data.