Matthias Brendel

Cerebrospinal fluid flow and clearance driven by lateral ventricle volume oscillations

This study shows that lateral ventricle volume oscillations drive CSF flow and clearance, influenced by cortical blood-volume changes and physiological drivers.

Anti-Aβ immunotherapy-mediated amyloid clearance attenuates microglial activation without inducing exhaustion at residual plaques

This study shows that long-term anti-Aβ treatment reduces amyloid plaques and microglial activation but leaves residual plaques with persistent immune activity.

Neuronal and oligodendroglial but not astroglial tau translates to in vivo tau-PET signals in primary tauopathies

This study shows that neuronal and oligodendroglial tau, but not astroglial tau, contribute to tau-PET signals in 4-repeat tauopathies.