Pietari Ripatti

Communicating polygenic and non-genetic risk for atherosclerotic cardiovascular disease - An observational follow-up study

This study evaluates the impact of communicating polygenic and clinical risk scores for ASCVD via a web tool, finding that high-risk individuals made more health behavior changes.

Polygenic and clinical risk scores and their impact on age at onset of cardiometabolic diseases and common cancers

The paper evaluates polygenic risk scores and clinical risk factors for predicting early-onset cardiometabolic diseases and cancers, showing comparable performance to clinical scores.

Polygenic risk score of alcohol consumption predicts alcohol-related morbidity and all-cause mortality

Genetics of human plasma lipidome: Understanding lipid metabolism and its link to diseases beyond traditional lipids

The paper conducts GWAS and PheWAS on plasma lipid species to identify genetic associations and their links to diseases beyond traditional lipid measures.

Polygenic Hyperlipidemias and Coronary Artery Disease Risk

This study assesses the association between polygenic risk scores for LDL-C and TG with CAD risk, finding a proportional relationship with lipid levels and partial independence from a CAD PRS.