Author

David H. Sochart

Epsom and St Helier University Hospitals NHS TrustORCID 0000-0002-6541-7187Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Angshumi Dutta· 2 shared Cíntia Scucuglia Heluany· 2 shared Giovanna NalessoiD· 2 shared Nicholas James DayiD· 2 shared Barbara A. FieldingiD· 1 shared Barbara Fielding· 1 shared Ioannis SmyrniasiD· 1 shared Vipin AsopaiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 24 mutual co-author links

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2 shared papersCell Biology

Angshumi Dutta

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2 papers

Recent·Most cited

CaMKII Activation Enhances Antioxidant Defence and Mitochondrial Function in human articular chondrocytes

Angshumi Dutta, Nicholas James Day, Cíntia Scucuglia Heluany, David H. Sochart, Barbara Fielding, Ioannis Smyrnias, Giovanna Nalesso

This study shows that activating CaMKII improves antioxidant defense and mitochondrial function in human articular chondrocytes under oxidative stress.

bioRxiv · May 28, 2026 · PreprintCell Biology

CaMKII induces an autophagy-dependent anabolic response in Articular Chondrocytes

Nicholas James Day, Angshumi Dutta, Cíntia Scucuglia Heluany, Vipin Asopa, David H. Sochart, Barbara A. Fielding, Giovanna Nalesso

This study shows CaMKII promotes anabolic processes and autophagy in chondrocytes while counteracting catabolic effects, but also drives hypertrophic differentiation in articular cartilage.

bioRxiv · Aug 4, 2024 · PreprintCell Biology