Author

Nicholas James Day

University of SurreyORCID 0000-0002-1553-8685Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 2 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Cíntia Scucuglia Heluany· 3 shared Giovanna NalessoiD· 3 shared Angshumi Dutta· 2 shared David H. SochartiD· 2 shared Anna De Palma· 1 shared Barbara A. FieldingiD· 1 shared Barbara Fielding· 1 shared David Sochart· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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3 shared papersCell Biology

Cíntia Scucuglia Heluany

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3 papers

Recent·Most cited

Cell BiologybioRxivPreprintMay 28, 2026

CaMKII Activation Enhances Antioxidant Defence and Mitochondrial Function in human articular chondrocytes

Angshumi Dutta, Nicholas James Day, Cíntia Scucuglia Heluany…·Giovanna Nalesso

This study shows that activating CaMKII improves antioxidant defense and mitochondrial function in human articular chondrocytes under oxidative stress.

DOI 10.64898/2026.05.27.727824

humanbulk RNA-seq

Pharmacology & ToxicologyOsteoarthritis and CartilagePeer-reviewedFeb 26, 2026

microRNA-544a as a new modulator of the Wnt-signalling network in the articular cartilage and osteoarthritis

Cíntia Scucuglia Heluany, Nicholas James Day, Keemo Delos Santos…·Giovanna Nalesso

This study identifies miR-544a as a modulator of Wnt signaling in OA chondrocytes, showing it enhances Wnt activation and promotes catabolism.

DOI 10.1016/j.joca.2026.02.010

humanbulk RNA-seq

Cell BiologybioRxivPreprintAug 4, 2024

CaMKII induces an autophagy-dependent anabolic response in Articular Chondrocytes

Nicholas James Day, Angshumi Dutta, Cíntia Scucuglia Heluany…·Giovanna Nalesso

This study shows CaMKII promotes anabolic processes and autophagy in chondrocytes while counteracting catabolic effects, but also drives hypertrophic differentiation in articular cartilage.

1 citation

humanbulk RNA-seq